Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1832
Gene Symbol: DSP
DSP 		0.300 SusceptibilityMutation disease ORPHANET Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. 23583980 2013
Entrez Id: 91039
Gene Symbol: DPP9
DPP9 		0.300 SusceptibilityMutation disease ORPHANET Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. 23583980 2013
Entrez Id: 23250
Gene Symbol: ATP11A
ATP11A 		0.300 SusceptibilityMutation disease ORPHANET Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. 23583980 2013
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR ATP-binding cassette member A3 (E292V) gene mutation and pulmonary morbidity in very-low-birth-weight infants. 22145626 2012
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome. 23166334 2012
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Structural and dynamic aspects of Ca2+ and Mg2+ binding of the regulatory domains of the Na+/Ca2+ exchanger. 22435821 2012
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Polymorphism analysis of the ABCA3 gene: association with neonatal respiratory distress syndrome in preterm infants. 22800827 2012
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Heterozygosity for E292V in ABCA3, lung function and COPD in 64,000 individuals. 22866751 2012
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR A child with severe pneumomediastinum and ABCA3 gene mutation: a puzzling connection. 22304854 2012
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B 		0.300 SusceptibilityMutation disease ORPHANET A variant in the promoter of MUC5B and idiopathic pulmonary fibrosis. 21506748 2011
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B 		0.300 SusceptibilityMutation disease ORPHANET A common MUC5B promoter polymorphism and pulmonary fibrosis. 21506741 2011
Entrez Id: 22861
Gene Symbol: NLRP1
NLRP1 		0.010 GeneticVariation disease BEFREE Logistic regression analysis showed an additive effect of IRF5 rs2004640, STAT4 rs7574865 and NLRP1 rs8182352 risk alleles on SSc-related FA. 21149496 2011
Entrez Id: 729238
Gene Symbol: SFTPA2
SFTPA2 		0.300 SusceptibilityMutation disease ORPHANET Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer. 19100526 2009
Entrez Id: 3663
Gene Symbol: IRF5
IRF5 		0.020 Biomarker disease BEFREE STAT4 and IRF5 act with additive effects in terms of susceptibility to both SSc and SSc-related fibrosing alveolitis. 19644887 2009
Entrez Id: 3663
Gene Symbol: IRF5
IRF5 		0.020 GeneticVariation disease BEFREE In a multivariate analysis model including the diffuse cutaneous subtype of SSc and positivity for anti-topoisomerase I antibodies, the IRF5 rs2004640 TT genotype remained associated with fibrosing alveolitis (P=0.029, OR 1.92, 95% CI 1.07-3.44). 19116937 2009
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.010 Biomarker disease BEFREE STAT4 and IRF5 act with additive effects in terms of susceptibility to both SSc and SSc-related fibrosing alveolitis. 19644887 2009
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Haplotype analysis of ABCA3: association with respiratory distress in very premature infants. 18246475 2008
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Population and disease-based prevalence of the common mutations associated with surfactant deficiency. 18317237 2008
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Aberrant catalytic cycle and impaired lipid transport into intracellular vesicles in ABCA3 mutants associated with nonfatal pediatric interstitial lung disease. 18676873 2008
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Clinical, radiological and pathological features of ABCA3 mutations in children. 18024538 2008
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Cerebropulmonary dysgenetic syndrome. 18603241 2008
Entrez Id: 7012
Gene Symbol: TERC
TERC 		0.310 SusceptibilityMutation disease ORPHANET Short telomeres are a risk factor for idiopathic pulmonary fibrosis. 18753630 2008
Entrez Id: 3565
Gene Symbol: IL4
IL4 		0.030 Biomarker disease BEFREE We correlated the transcription of TGF-beta(1), connective tissue growth factor (CTGF), IL-4, IL-13 and interferon-gamma (IFN-gamma) with lung function development in progressive fibrosis in idiopathic interstitial pneumonia. 18525195 2008
Entrez Id: 3596
Gene Symbol: IL13
IL13 		0.020 Biomarker disease BEFREE We correlated the transcription of TGF-beta(1), connective tissue growth factor (CTGF), IL-4, IL-13 and interferon-gamma (IFN-gamma) with lung function development in progressive fibrosis in idiopathic interstitial pneumonia. 18525195 2008
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.010 Biomarker disease BEFREE We correlated the transcription of TGF-beta(1), connective tissue growth factor (CTGF), IL-4, IL-13 and interferon-gamma (IFN-gamma) with lung function development in progressive fibrosis in idiopathic interstitial pneumonia. 18525195 2008